Ovarian cystic teratoma is radiologically easily diagnosed due to calcification or fat, for example, but the preoperative diagnosis of struma ovarii is often difficult due to rare characteristic features of thyroid tissue.
Struma ovarii is ovarian tumor composed solely or predominantly of thyroid tissue or tumor in which hyperthyroidism results from ovarian thyroid tissue, and usually occurs in tandem with cystic teratoma.
Kim, Jong Chul Shin, Hyun Ja Kim, Seung Hyup Byun, Jae Young International Nuclear Information System (INIS) There were, however, no specific radiologic findings that were sufficiently typical to suggest the correct preoperative diagnosis of struma ovarii. In one patient, hyperthyroidism was caused by struma ovarii. Most cases of struma ovarii occurred unilaterally within ovarian teratomas in premenopausal women, and were mixed cystic and solid masses with smooth margins that are commonly enhanced on contrast enhanced scans. In one patient with hyperthyroidism due to struma ovarii, symptoms and signs of this subsided after removal of the tumor on salpingo-oophorectomy. Malignant change or metastasis was not found in any tumor. Calcifications were found in two tumors, and fat in one. Three of four cystic masses (one unilocular, one bilocular and two multilocular cysts) had mural nodules. All eleven tumors were unilateral, ten had smooth tumor margins, seven were mixed cystic and solid tumors (more than 70% of solid components in one tumor), and nine had regular septa. These findings were compared with pathologic findings. Using ultrasonography, computed tomography, and magnetic resonance imaging, preoperative radiologic findings of pathologically-proven struma ovarii in eleven patients were retrospectively evaluated for site, margin, nature (cystic, solid, mixed), contrast enhancement, septa, mural nodule, calcification, fat, and metastasis. Our purpose was to determine whether there were specific findings of struma ovarii which distinguished it from other ovarian tumors, and this involved analysis of its radiologic findings. College of Medicine, Seoul (Korea, Republic of) College of Medicine, Seoul (Korea, Republic of) Byun, Jae Young [Catholic Univ. School of Medicine, Taejeon (Korea, Republic of) Shin, Hyun Ja [Korea Veterans Hospital, Seoul (Korea, Republic of) Kim, Seung Hyup [Seoul National Univ. We report the case of a 36-year-old woman who presented with clinical signs and symptoms of hyperthyroidism as well as a left adnexal mass, which proved to be a thyroid hormone-producing, malignant struma ovarii.Įnergy Technology Data Exchange (ETDEWEB) Only isolated cases of hormonally active papillary thyroid carcinoma developing within a struma ovarii have been reported in the literature. Less than 8% of struma ovarii cases present with clinical and biochemical evidence of thyrotoxicosis due to ectopic production of thyroid hormone and only 5% undergo malignant transformation into a papillary thyroid carcinoma. A Hormonally Active Malignant Struma Ovariiĭirectory of Open Access Journals (Sweden)įull Text Available Struma ovarii is a rare monodermal variant of ovarian teratoma that contains at least 50% thyroid tissue.
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